From the 1600s, enslaved people, and after abolition of slavery, indentured labourers were transported to work on plantations in distant European colonies. Inhuman conditions and new pathogens often resulted in disease and death. Central to this book is the encounter between introduced and local understanding of disease and the therapeutic responses in the Caribbean, Indian and Pacific contexts. European response to diseases, focussed on protecting the white minority. Enslaved labourers from Africa and indentured labourers from India, China and Java provided interpretations and answers to health challenges based on their own cultures and medicinal understanding of the plants they had brought with them or which they found in the natural habitat of their new homes. Colonizers, enslaved and indentured labourers learned from each other and from the indigenous peoples who were marginalized by the expansion of plantations.