The latest disruptive innovation that has brought a potential change and revolution in the existing higher education system is Massive Open Online Courses (MOOC). MOOC is one of the acceptances and advantages of OER activity in Malaysia. Students can select what they want to learn, like customized learning. They attend their class at home, by watching videos, answering questions, quizzes via online learning. Hence, MOOC is a new form of online learning with technology enhancement that provides open training and instruction to all global students without charges and is recently a new trend of personalized learning situations either at colleges or higher education institutions. The instantaneous development of MOOC offers universities a platform to deliver learning content with innovation and explore new pedagogical experiences and flexible learning paths in Malaysia. This book mainly provides key success factors, management strategies, and sustainable development of MOOC implementation in Malaysia. The book also introduces the higher education system in Malaysia, including online learning, distance learning, and electronic learning which are integrated and implemented in the higher education institutions. Through discussions of online learning and MOOC implementation worldwide instead of in Malaysia, the book navigates the key success factors, issues, and challenges of MOOC implementation. The book also describes the MOOC initiatives and status of implementation from multiple case studies and scholarly reports. By analyzing the MOOC initiative in Malaysia, the book offers insights into government policies, and management strategies for a successful MOOC implementation. The chapters also offer the theoretical and practical implications of MOOC implementation in the Malaysian higher education system. The valuable contributions of other scholars’ studies will be described and MOOC implementation toward sustainability development for the globalized Malaysian education system will be discussed. This book may represent limiting but important factors for the implementation of MOOC in Malaysian universities. The MOOC providers and senior management team may gain some valuable insights to manage, organize, and think carefully to provide appropriate and good quality MOOCs in Malaysian universities as it will be used by students globally.