Entrepreneurial leadership of Indigenous People (IP) focuses on using pre dispositions, behaviors, and skills used to spot opportunities and exploit themfor the existing resources and contexts and not on adapting their organizations. This study explored the entrepreneurial leadership and practices of the IPs: ATis (Aetas) in Dumarao, CApiz, Philippines; and Maduranese in Indonesia towardseconomic development and social advancement. This was a qualitative research. It was found that the Atis have poor indigenous leadership and no organized business enterprise in Dumaro.In marketing their items, purchasers obtained them at low costs.Conversley, the Maduranese have entrepreneurial mindset,very receptive to their society, do not see poverty as a hindrance to growth and development, and made ways to sustain their standard of living if there is an opportunity.