Education and science are foundational to international development, yet gender inequities in Science, Technology, Engineering, and Mathematics (STEM) persist globally. While these disparities are widespread, most research and discourse on gender in STEM originates from the Global North. This edited collection amplifies contributions from the Global South, presenting twelve case studies supported by Canada’s International Development Research Centre (IDRC). The case studies are led by researchers across Africa and Latin America who investigate gender inequities in STEM within their local or regional contexts.